Medication albendazole or mebendazole
Albendazole (Albenza) is used to treat infections caused by worms like pinworms. Albendazole works by keeping the worm from absorbing sugar (glucose), so that the pinworm loses energy and dies.
In some patients, pinworms may return after treatment with albendazole. Treatment may be repeated after 3 weeks.
Treatment with albendazole for pinworm infection is a single tablet, which kills the worms. There are different strengths for adults and children younger than two years of age.
Albendazole is available only with your doctor's prescription. It may be used in cases of threadworm infections that cannot be treated with other medications. It is not the medicine usually first used to treat enterobius vermicularis infections.
Albendazole is not recommended for use in pregnant women or in people with poorly functioning livers.
Mebendazole or MBZ is a benzimidazole drug developed by Janssen Pharmaceutica and marketed as Vermox, Ovex, Antiox, and Pripsen. It is used to treat infestations by worms including pinworms, roundworms, tapeworms, hookworms, and whipworms.
Mebendazole (Vermox) also works to get rid off pinworms. It is taken in a single dose like albendazole and repeated two weeks later.
Because it is common for everyone in a household to have pinworms at the same time, the doctor may recommend that everyone be treated at the same time with mebendzale.
Previously used drugs, pyrantel pamoate and piperazine, are now rarely used for pinworm removal due to lower efficacy and a higher frequency of side effects compared to albendazole (Albenza) or mebendazole (Vermox). Pyrantel pamoate is a depolarizing neuromuscular blocking agent, inhibits cholinesterases, resulting in spastic paralysis of the worm.
Thiabendazole is a generic medication that treats intestinal worms, including pinworms. It kills parasites that invade the body.
The dosage of thiabendazole depends upon body weight. Patients might take the drug from two days up to seven days, depending on the type of parasite. It comes in liquid and tablet forms, with the tablet typically chewed after a meal.
Taking the medication on a full stomach might help prevent nausea, vomiting or dizziness associated with the drug. A person might also feel bloated and pass excessive gas. Some people vomit, lose weight and feel tired most of the time. An itchy rectum is another sign that worms might be present, along with seeing worms in the stool.